First, about mana regeneration. Nothing has really been taken away from a level 30 summoner with Meditation and yellow mp5 glyphs. We liked that approximate pacing for mana regen, but the difference between having that and not was simply too high (...) Yellow and blue clarities now provide slightly less mana regeneration, but all champions have had their base regenerations per level incresed [sic] too. Only if you take yellows and blues will you see a slight loss in mp5, and only after around level 5 or so.
(...) We didn't like the amount you had without [MP5 runes / masteries], so we buffed base mana regens substantially. But in that case, the amount of regen you had with those runes/mastery was too high, so they had to be reduced to make sure you couldn't get too much. So it's pretty much a breakeven now if you take them, and a win if you don't.
Doran's items were compensated in stats for their increase in cost, so it's not a net loss. (...) I think overall there will be a bit less health overall (...). But it's harder to have lots of starting health, mitigation, and tons of regen.
Rammus is getting a small nerf to the effects of the Powerball slow as well as the fix to taunt cooldown.